cd40 ligand การใช้

More specifically, Lentiviruses attach to the CD40 ligand glycoproteins on the surface of T-lymphocyte cells.
CD40 ligand is primarily expressed on activated CD4 + T lymphocytes but is also found in a soluble form.
SAg activation in T-cells leads to production of CD40 ligand which activates isotype switching in B cells to IgG and IgM and IgE.
Despite the setbacks, IDEC Pharmaceuticals of San Diego is now testing its own antibody against the same target _ known as CD40 ligand _ in psoriasis and other autoimmune diseases.
TLR10's mechanism of action is not yet known but activation of the receptor has been shown to suppress NF-kB, MAP kinase and Akt signaling events stimulated by TLR and CD40 ligands.